Bacterial co-infection has been frequently reported in the influenza disease

Bacterial co-infection has been frequently reported in the influenza disease, while co-infection has been rarely seen in patients with SARS-CoV-1, and evidence show that co-infection does not occur in patients with MERS-CoV. The limited studies have assessed co-infection in patients who suffer from SARS-CoV-2, and they show different results. In a study, 73 intubated patients who suffered from COVID-19 and were admitted to three ICUs of Al-Zahra hospital, Isfahan were assessed for bacterial co-infections. 43% patients had bacterial co-infection that was mainly caused by Klebsiella sp. and Acinetobacter sp. A significant relationship was seen between co-infection and length of hospital stay until intubation. A critical issue was that despite the frequency of bacterial co-infection in 43% of patients, antibiotic was used for 97.3% of subjects.